Chronic inflammation is fueled by a trio — dysfunctional immunity, defective gut barrier, and dysbiotic microbiome

Photo by Umesh R. Desai on Unsplash

Chronic inflammation is the central player in the most challenging health conditions of our time. You name it — obesity, diabetes, cancer, rheumatoid arthritis, bowel diseases, heart diseases, asthma, and even mental disorders — sustained inflammation is the critical underlying factor in all of these chronic immune and metabolic conditions that significantly compromises our quality of life.

Inflammation in itself is not a villain as it is our body’s essential survival mechanism to fight-off pathogens and repair injured tissues. So how does this friend to foe make our life miserable and play an important role in these chronic health conditions?


Excellent article with practical approaches to the topic. Thoroughly enjoyed reading.


Synbiotics for Building a Healthy Gut Microbiome

Image by ErikaWittlieb from Pixabay

Dietary strategies like the food and supplements rich in probiotics and prebiotic dietary fibres are a powerful tool to nourish the gut health. They support and feed the 100 trillion microorganisms that reside in our gut, the infamous “gut microbiota” that in turn bestow us with health and immune benefits.

But the combination of probiotics and prebiotics — called synbiotic is a powerful strategy that you can apply to harness the maximum advantages the synergism between probiotics and prebiotics has to offer, especially in the case of chronic health conditions. …


I am a Biomedical Researcher interested in inflammation and microbiome for gut health and beyond . Published Academic author . Gut Health Evangelist . Mom . Reader .


The microbes in our gut signal the brain to decide what foods we should crave for

Image by Ryan McGuire from Pixabay

If you find it next to impossible to resist the 3 p.m. sugar cravings, that hit you every day and you end up blaming yourself for your lack of self-control, let me tell you, it’s the bugs in your gut that tempt you to eat doughnuts and cakes.

Scientists are at task trying to understand how it is not our “self-control” but the “microbes” residing in our gut (gastrointestinal tract) that controls our appetite and cravings.

Let’s try to understand how do they do this and how we can control them instead of them controlling what we crave for.

Don’t…


You will not regret.

Image by Ivana Divišová from Pixabay

We all want success in anything and everything we do. No one wants to fail. Failure happens, without us wanting it to happen. But failure has the power to make you successful if you use it to your advantage.

Okay, let me ask you a question: would you take a chance to attempt driving a car with broken headlights at night? I guess not. And that's because you anticipate the danger and the risk involved in taking such an action. Foreseeing or predicting the risk makes it useful for you to make appropriate decisions.

We are trained (consciously and unconsciously)…


Extreme environmental stressors during spaceflights affect astronaut’s health

Photo by Brian McGowan on Unsplash

Travelling long distances can be tough on the body, and if it is on the Mars or Moon you are travelling to, it can take a serious toll on your overall health — body and mind included. It might look cool and fun to go on the space voyages in those fancy air-craft as we see in the movies, but in reality, they are excruciating, long and far from being fun.

Space-flight stressors affect the health of astronauts

According to NASA, there are five main hazards of human spaceflight: radiation, gravity, distance from Earth, hostile enclosed environments, and isolation. Spending time in the low gravity environment of…


Fibre feeds your gut microbiome and carbs affect blood glucose

Image by Gerhard G. from Pixabay

A low-carb diet is a buzz word most of us are familiar with. It has gained popularity with scientific evidence supporting its benefits in losing weight and controlling blood sugar, among other benefits.

A low-carb diet generally means that you eat fewer carbohydrates and a higher proportion of fat and an adequate amount of protein — low-carb-high-fat diet or ketogenic (keto) diet.


A road towards immune fitness with functional diet — prebiotic, probiotic and synbiotic

If “health is wealth”, then the treasure box for that wealth is your gut. Guarding this treasure box full of potential health benefits is an army of about 100 trillion microbes that reside in our gastrointestinal tract, infamously known as the “gut microbiota”. They hold immense power in unlocking this treasure box.

You favor the right microbes to flourish, and you are in for cashing out all the immune health benefits for a happy and healthy life. …


Both share a common feature of imbalanced approach: wheels and immunity

Photo by Greg Boll on Unsplash

Our immune system is like a bicycle. It has two wheels — innate immunity and adaptive immunity. When it is under attack by a pathogen, it gears up to take you on a ride to recovery. The ride is either smooth or bumpy depending on the condition and/or size of the wheels.

Tanvi Shinde, PhD

. Biomedical Researcher interested in inflammation and microbiome for gut health and beyond . Published Academic author . Gut Health Evangelist . Mom . Reader .

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